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Immunofluorescence Testing

Contact Information

UCSF Dermatopathology Service

1701 Divisadero Street, Suite 280
San Francisco, CA 94115

Telephone: 415-353-7546
Toll-free: 800-497-0244
Fax: 415-353-7543

Immunofluorescence is a proven way to diagnose immunologic disorders such as:

  • Blistering diseases (Bullous Pemphigoid)
  • Connective tissue diseases (Lupus Erythematosus)
  • Vasculitis (Henoch-Schonlein Purpura)

M. Kari Connolly, M.D. leads our Immunofluorescence service with her expertise in autoimmune skin diseases and immunofluorescence testing. She also directs the autoimmune skin disease clinic at UCSF where she sees patients with complex autoimmune diseases.

Dermatopathology and immunofluorescence testing play key roles in the diagnosis and classification of immunologic disorders, helping you provide superior care to your patients. You will have direct contact with M. Kari Connolly, M.D. regarding your cases.

We Offer:

• Fast turn around time 24 – 48 hours
• DIF performed on skin, mucosa and ocular tissue
• Processing at our state-of-the-art CLIA approved lab
• Accurate, concise reporting with histology correlation
• Photographs available upon request
• Direct communication with M. Kari Connolly M.D. (415) 476-7927

Sending a specimen for Immunofluorescence Testing:

Direct Immunofluorescence
Place tissue specimen into the green direct immunofluorescence vial that we provide.  Store at room temperature. Complete requisition form, and mail. See Biopsy Site Guidelines below for more information.

Indirect Immunofluorescence
Draw blood into a serum-separator tube and store at room temperature. Ideally, draw about 5cc's. If a tech can spin and separate off the serum (1 to 2cc's), that is ideal. If not, we will spin it here. Complete requisition form, and mail.

Click the below PDF links for more detailed information regarding DIF biopsies:

Direct_Immunofluorescence_Biopsy Site Guidelines


Immunofluorescence Supplies
Click Here to order supplies online or call to request complimentary Direct Immunofluorescence bottles, requisition forms, and preprinted FedEx Airbills (courier service available for offices located in the Greater San Francisco Bay Area).
Local: (415) 353-7546. Toll Free: (800) 497-0244

Mail DIF cases to:
UCSF Dermatopathology Service
1701 Divisadero St. Suite 280
San Francisco, CA 94115

The University of California, San Francisco. ©2014 The Regents of the University of California
UCSF Dermatopathology Service | 1701 Divisadero St. Suite 280 | San Francisco, CA 94115
Phone: 415-353-7546 Toll Free: 800-497-0244 Fax: 415-353-7543
CLIA ID: 05D0669292

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